At least with these drugs there is somewhat of an understandable reason for the confusion. First of all, only a relatively small percentage of bodybuilders have ever used higher-dose pharm-grade growth hormone for even a short period of time, let alone over the long-term, simply because it is too expensive for most to afford. This removes personal experience from the equation, automatically leaving 99%+ of all bodybuilders susceptible to the influence of fairy tales. Secondly, not all pharm-grade growth hormone is synthesized in the same fashion, which is the reason why different brands can provide different cosmetic effects. Anyone who has experience using multiple brands of GH will confirm that they do not all affect the body in the same way from a visual standpoint. Some cause significant water retention, while others cause much less by comparison.
RAD 140 : Testolone studies are still being produced, but it has been known to have equal potency and effectiveness to that of LGD4033. Dosages ranged between 20mg to 30 mg per 24-36 hours for maximum skeletal muscle hypertrophy. Safe durations for research have been tolerated for up to 12 weeks, however, developing trials may indicate tolerance for up to 24 weeks. It is important to note that RAD140 systematically regulates the neuroexcitatory amino acid Kainate which activates glutamate receptors in the brain. Kainate acid’s role in neuronal cell death (specifically in the hippocampus) has been shown to be a primary contributor to Alzheimer’s disease. RAD140 has demonstrated positive results in the prevention of Kainate acid production and medical based research published by The Endocrine Society suggests RAD140 can improve brain health through neuroprotective properties in as little as 13 days (Jayaraman, 2014). This characteristic of nonsteroidal SARMs is not added in the General Benefits section of this article because it is exclusive only to RAD140.
For women, things are a bit different. They do not need SERMs because they produce so little testosterone naturally that suppression isn’t as detrimental. However, Anavar and Winstrol act much like testosterone in the female body, and using the combination over the course of four to six weeks can create a hormonal imbalance. Women who simply come off steroids cold turkey, even after a few weeks, may notice undesirable effects like fatigue and irritability. To avoid this, simply reducing dose toward the end of the cycle can help tremendously.