Anticoagulants: Patients on anticoagulants such as warfarin should be carefully monitored during anabolic steroid therapy as anabolic steroids may increase sensitivity to oral anticoagulants which may require a concomitant reduction in anticoagulant dosage to achieve a desirable prothrombin time (PT). Anticoagulant patients should be monitored regularly during anabolic steroid therapy, particularly during initiation and termination of therapy. Warfarin patients should have INR and PT monitored throughout androgen therapy and warfarin dosages titrated to achieve the desired INR and PT. Such patients should be monitored for occult bleeding.
Anavar is a Dihydrotestosterone derivative , which prevents it from interacting with the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. As a result, one can expect very solid lean muscle gains without any water retention, and minimal fat gain/retention (provided the user has accompanied their cycle with an appropriate diet). Due to Anavar’s anabolic rating of 322 – 630 (the strength of at least 3 times that of Testosterone ), it can and will also elicit dramatic strength gains and considerable lean mass addition.