Oxandrolone and pregnancy

The oral bioavailability of oxandrolone is 97%. [2] Its plasma protein binding is 94 to 97%. [2] The drug is metabolized primarily by the kidneys and to a lesser extent by the liver . [1] [2] Oxandrolone is the only AAS that is not primarily or extensively metabolized by the liver, and this is thought to be related to its diminished hepatotoxicity relative to other AAS. [1] [3] Its elimination half-life is reported as to  hours but is extended to  hours in the elderly. [2] [3] Approximately 28% of an oral dose of oxandrolone is eliminated unchanged in the urine and 3% is excreted in the feces . [3]

Alcohol consumption may exacerbate liver injury caused by other pathogenic factors, including hepatitis viruses. Approximately 20% of patients presenting with alcoholic hepatitis have concomitant hepatitis C virus infection. [ 7 ] Extensive epidemiologic studies suggest that the risk of cirrhosis in patients with chronic hepatitis C infection is greatly exacerbated by heavy alcohol ingestion. Possible mechanisms include the impairment of immune-mediated viral killing or enhanced virus gene expression due to the interaction of alcohol and hepatitis C virus.

Oxandrolone and pregnancy

oxandrolone and pregnancy


oxandrolone and pregnancyoxandrolone and pregnancyoxandrolone and pregnancyoxandrolone and pregnancyoxandrolone and pregnancy